Open access
Jul 2026
Processing-Optimized Multi-Epitope mRNA Vaccine Enhances HIV-1—Specific CD8+ T Cells 2258806
An mRNA vaccine encoding tandem CD8+ T-cell epitopes with optimized flanking sequences elicited quantitatively and qualitatively superior epitope-specific CD8+ responses in HLA-A*02:01 mice and in PBMCs from people with HIV-1.
T. Nogimori, H. Nguyen, M. Kumamoto et al.
· Journal of Immunology · 0 citations