Co-Administration of Novel Oral Polio Vaccine Type 2 and Bivalent Oral Polio Vaccine: Current Evidence, Challenges, and Implications for the Polio Eradication Endgame
Abstract Global polio eradication is challenged by persistent wild poliovirus type 1 (WPV1) transmission and outbreaks of circulating vaccine-derived poliovirus type 2 (cVDPV2). The 2016 global withdrawal of the type 2 component from trivalent oral poliovirus vaccine (tOPV) created population immunity gaps, facilitatin...