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Author

Tanja Vogel

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Open access Sep 2026

Epigenetic perturbation unravels diverse origins, state conversions and de-differentiation of cortical astrocytes

DOT1L is established as a barrier between these astrocyte states, limiting differentiation of the astrocytes expressing phagocytosis marker genes, and lowering the DOT1L-mediated epigenetic barrier strongly favours appearance of astrocytes with limited phagocytosis properties and reactivation of progenitor programs.

Maira Mirza, Tobias Hohl, Camila L. Fullio et al. · 0 citations
Open access Jul 2026

Regulation of protein abundance in neurons by selective translation of 3′UTR isoforms

3′UTR-mediated translational control is proposed as an evolutionarily conserved mechanism for the maintenance of cell-type-specific proteostasis for the maintenance of cell-type-specific protein synthesis in neurons.

Sakshi Gorey, Hasan Can Ozbulut, Judit Carrasco et al. · 0 citations

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