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Tao Chen

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Open access Sep 2026

A nutrient-sensing protease DegS suppresses biofilm formation in Vibrio cholerae via the CdgH–c-di-GMP–VpsR axis under nutrient limitation

Findings reveal DegS as a key upstream sensor that translates nutrient scarcity into a precise inhibitory signal via c-di-GMP-dependent transcription, providing new insights into the molecular basis of V. cholerae environmental adaptation and highlighting a potential target within its transmission chain.

Xiao-Yu Huang, Tao Chen, Qi-Qi Linghu et al. · 0 citations

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