Sep 2026
A Progression-Associated Tumor-Reactive T-Cell Signature Predicts Immunotherapy Response and Reveals ICOS-High CD8 T-Cell Functional States in Head and Neck Squamous Cell Carcinoma.
Immune checkpoint blockade has improved outcomes for patients with head and neck squamous cell carcinoma (HNSCC), but reliable biomarkers for predicting therapeutic response remain limited. Tumor-reactive T-cell states are increasingly recognized as critical determinants of antitumor immunity; however, progression-asso...
Shao-Qian Zhang, Xiao-Tong Yan, Xi-Chen Dong et al.
· Molecular Carcinogenesis · 0 citations