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Tao-Tao Chen

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Open access Aug 2026

Coxiella burnetii inhibits host cell death by ubiquitination‐induced inactivation of an apoptosis nuclease

Abstract Coxiella burnetii modulates a variety of host cell processes to create a niche permissive for its intracellular replication using effectors injected by its Dot/Icm type IV secretion system. More than 130 such effectors have been identified, but the function of most of them remains unknown. Using an activity‐ba...

Yong Zhang, J. Jiao, Shuxin Liu et al. · 0 citations
Open access Aug 2026

Crystal structure of Legionella pneumophila glycosidase effector LegY.

Structural insights are provided into LegY, laying a foundation for future uncovering of its putative function during L. pneumophila infection, suggesting possible horizontal gene transfer or convergent evolution.

Jing Chen, Fan Li, Shao-Yuan Wang et al. · 0 citations

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