Tao Zhang

Collective Cell Fluidity Controls Active Prestress Transmission in Cell-Extracellular-Matrix Tissues

Tissues are active composites in which multicellular collectives and extracellular matrices mechanically reorganize one another. We develop a three-dimensional micromechanical model that couples deformable, rearranging cell clusters to a disordered network of semiflexible fibers through a dynamic, force-generating inte...