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Author

Taotao Tan

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Open access Aug 2026

Defining the Early Response of Oligodendrocyte-Lineage Cells to Traumatic CNS Axonal Injury.

Injured central nervous system axons rarely regenerate or remyelinate efficiently. Oligodendrocyte (OL) -lineage cells influence both processes, yet their early response to axonal injury remains incompletely defined. Using an optic nerve crush model in male and female mice, we profiled acute OL-lineage responses over t...

Yu Wu, Xiaoyun Ding, Jiaxing Li et al. · 0 citations
Open access Jul 2026

Kernelized approach enables explainable gene prioritizations for complex traits

Genome-wide association studies (GWAS) have identified numerous variant-trait associations; yet, assigning effector genes to GWAS loci remains challenging. Similarity-based machine-learning methods, such as PoPS, prioritize effector genes from shared functional profiles among trait-relevant genes. These models assign a...

Taotao Tan, Md. Abul Hassan Samee · 0 citations

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