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Author

Taro Yamashita

3 papers indexed here

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Sep 2026

Abstract A088: EphA2 Proteolytic Fragment Links Early Detection, IPMN Progression, and Therapeutic Resistance in Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) remains highly lethal because most patients are diagnosed after curative intervention is no longer feasible and resistance to systemic therapy is common. Intraductal papillary mucinous neoplasms (IPMNs) are important PDAC precursor lesions, but serum biomarkers for early PDAC d...

Naohiko Koshikawa, S. Sato, Kazuki Ikeda et al. · 0 citations
Open access Sep 2026

Distinct metabolomic signatures of SGLT2 inhibitor vs. sulfonylurea in a paired human liver biopsy study

This study aimed to elucidate how sodium-glucose cotransporter 2 (SGLT2) inhibitors and sulfonylureas differentially modulate hepatic metabolism in persons with metabolic dysfunction-associated steatotic liver disease (MASLD) and type 2 diabetes (T2D). In this 48-week randomized, open-label, parallel-group trial, Japan...

Y. Takeshita, Hein Ko Oo, Yujiro Nakano et al. · 0 citations

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