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Tatsuya Yamamoto

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Open access Sep 2026

A Practical Workflow for Reliable MALDI-Based Hydrogen/Deuterium Exchange Mass Spectrometry

Matrix-assisted laser desorption/ionization-based hydrogen/deuterium exchange mass spectrometry (MALDI-HDX-MS) can provide peptide-level information on protein conformational dynamics without any specialized liquid chromatography (LC)-HDX instrumentation. Accurate interpretation of structure-dependent deuterium incorpo...

Tatsuya Yamamoto, H. Satake · 0 citations

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