Author

Tatyana I. Kovyanova

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Review Open access Oct 2026

Irisin in Cardiovascular Health and Disease: A Review of Its Function as a Biomarker and Therapeutic Target in Atherosclerosis and Related Conditions

Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of mortality worldwide, necessitating novel biomarkers and therapeutic targets. Irisin, a myokine derived from FNDC5, has emerged as a molecule of interest owing to its pleiotropic effects, yet its role in cardiovascular health is debated amid con...

S. Dabravolski, S. Shityakov, Nikita A. Mitkin et al. · Current Issues in Molecular... · 0 citations

Review Open access Sep 2026

Perspectives of Natural Products and Sialic Acid Mimetics as Modulators of Human Sialidases NEU1–3 in Atherosclerosis

This narrative review summarizes current data on the role of desialylation of low-density lipoproteins (LDL) as a key initiating mechanism of atherogenesis that precedes oxidative modification. The structural and functional significance of sialic acid in apolipoprotein B-100 is considered, and the enzymes of the sialid...

Tatyana I. Kovyanova, V. P. Karagodin, D. Borodko et al. · Biomolecules · 0 citations

Review Open access Aug 2026

Non-Pharmacological Strategies in Atherosclerotic Cardiovascular Disease: From Molecular Mechanisms to Clinical Integration

Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of morbidity and mortality worldwide, driven by complex interactions among dyslipidemia, chronic inflammation, insulin resistance, endothelial dysfunction, and gut microbiome-derived metabolites. This review synthesizes mechanistic and clinical ev...

Tatyana I. Kovyanova, M. Nerush, V. P. Karagodin et al. · Biomedicines · 0 citations