Systemic energy and neuroinflammatory disturbances in a lactacystin-induced rat model of Parkinson's disease.
Energy and neuroinflammatory disturbances in the blood and brain tissue were studied in a rat model of Parkinson's disease (PD) induced by a double bilateral injection of the ubiquitin-proteasome system (UPS) inhibitor, lactacystin (LC), into the substantia nigra pars compacta (SNpc) of the brain. Experimental modeling...