Open access
Aug 2026
Hepatic ChREBP Drives Cardiac Remodeling via ApoM Non-transcriptional Repression
BACKGROUND: Pathological cardiac remodeling is a hallmark of numerous cardiovascular diseases and develops into heart failure. As a systemic disease, effective treatments for cardiac remodeling from a tissue crosstalk perspective are still significantly unmet. METHODS: Hepatocyte-specific ChREBP (carbohydrate response...
Shuang Zhang, Zhen-zhen Zhang, Zi-Han Ma et al.
· Circulation Research · 0 citations