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Teppei Niide

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Jul 2026

Rational Thermostabilization of the Fe(II)/α-Ketoglutarate-Dependent Halogenase BesD While Preserving Halogenation Selectivity.

Fe(II)/α-ketoglutarate (αKG)-dependent halogenases that catalyze site-selective C-H halogenation of free substrates without carrier proteins are attractive biocatalysts for diversifying pharmaceuticals and agrochemicals. However, their application remains limited by the narrow diversity of natural halogenases, poor sta...

Teppei Niide, Keita Miyawaki, Hyuga Miyamoto et al. · 0 citations

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