Review
Open access
Aug 2026
Beyond Neurodegeneration: White Matter Vacuolation as a Primary Myelin Defect
Spongiform degeneration, or status spongiosis, is characterized by vacuoles within the central nervous system. It appears in numerous neurological diseases, including transmissible spongiform encephalopathies, mitochondrial disorders, and lysosomal storage diseases. Traditionally considered secondary to neurodegenerati...
Snehajit Misra, Teresa M. Gunn
· International Journal of Mol... · 0 citations