Sep 2026
Integration of network pharmacology, structure-based pharmacophore modeling, DFT, molecular docking, and molecular dynamics simulations to identify multi-target small molecule inhibitors against Alzheimer's disease.
The findings of this study suggest that Hit1 could be a promising multi-target molecule capable of modulating cholinergic transmission, neuronal survival pathways, and oxidative stress in AD.
D. O. Onwu, R. Oria, Y. A. Adekunle et al.
· Naunyn-Schmiedeberg's Archiv... · 0 citations