Open access
Sep 2026
Reduced HMGCR Expression in Clear Cell Renal Cell Carcinoma Is Associated With Poor Patient Prognosis
Background/Aim Renal cell carcinoma (RCC) is a heterogeneous malignancy, with clear cell renal cell carcinoma (KIRC) being the most common subtype, characterized by von Hippel–Lindau (VHL) tumor suppressor gene inactivation and hypoxia-inducible factor (HIF) pathway activation, leading to enhanced angiogenesis and tumo...
Etsushi Akitaya, Yuzuki Nakamura, Shiho Kato et al.
· Cancer Diagnosis & Prognosis · 0 citations