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Author

Thanh D. Do

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2 papers indexed here

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Aug 2026

Early Hetero-Oligomerization of Tau Fragments Redirects Cofactor-Free Tau Assembly and Fibril Morphology

Early tau assembly intermediates are increasingly recognized as bioactive species that govern downstream aggregation and cellular dysfunction, yet it remains unresolved whether distinct tau fragments directly interact during these early stages to redirect pathway selection. Here, we use a cofactor-free two-peptide mo...

Happy Abena Safoah, Sarah Hirschbeck, Jie Chen et al. · 0 citations
Review Open access Jul 2026

Beyond Sequence: Posttranslational Remodeling of Antigens in Autoimmunity

Autoimmune responses are often attributed to failed tolerance to self‐proteins, yet protein expression alone cannot explain why certain antigens dominate disease, why autoreactivity emerges under stress, or why specific HLA alleles shape risk. This review presents a framework in which autoimmunity arises from posttrans...

Cynthiya Shrestha, Holly M. Weisfelder, Thanh D. Do · 0 citations

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