IFNG rs2430561 polymorphism and its association with disease onset, cutaneous severity, and activity in Vietnamese patients with lupus erythematosus.
Interferon (IFN)-γ plays a central role in lupus pathogenesis, and the IFNG rs2430561 (+874 T/A) polymorphism has been linked to systemic lupus erythematosus (SLE) in several populations. This study investigated the association of rs2430561 with disease onset, cutaneous severity, and global activity in Vietnamese patie...