Preparation of resveratrol nanocrystals by drug/polymer/surfactant ternary hot extrusion
Drug nanocrystal formulations are an effective strategy for dissolution improvement and oral absorption of poorly water-soluble drugs. In our previous study, we developed a ternary hot extrusion method and demonstrated that drug nanocrystal suspensions can be successfully prepared. In this study, resveratrol (RES) was...