Deletion of peptidyl-tRNA hydrolase reshapes translational homeostasis and envelope-associated stress responses in Acinetobacter baumannii.
Acinetobacter baumannii is a critical multidrug-resistant pathogen responsible for severe nosocomial infections worldwide. Maintenance of translational quality control is essential for bacterial fitness under stress conditions. Peptidyl-tRNA hydrolase (Pth) rescues stalled ribosomes by hydrolyzing peptidyl-tRNA, thereb...