Open access
Sep 2026
Integrative multi-omics analysis reveals lipid/metabolite dysregulation and temporal decoupling in disease progression
Key metabolic control points (ceramide accumulation, arginine flux diversion, autophagy–lipid cross-talk, NAD⁺ salvage timing) were identified, highlighting potential targets for stage-specific therapeutic or nutritional interventions.
Uchenna Alex Anyaegbunam, V. ten Cate, Katrin Bauer et al.
· Scientific Reports · 0 citations