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Author

Thirupathi Ravula

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Open access Aug 2026

Molecular mechanisms governing peptide nanodisc assembly and stability.

Using coarse-grained molecular dynamics (CG-MD), this work captures the de novo formation of 4F nanodiscs with DMPC and reveals a multistep assembly pathway involving nucleation, fusion, and ellipse-to-disc maturation, validating the ability of CG-MD to resolve nanodisc assembly mechanisms.

Bikash R. Sahoo, B. Krishnarjuna, Thirupathi Ravula et al. · 0 citations
Review Open access Aug 2026

Nanodiscs for drug delivery.

This review discusses the recent developments of lipid nanodiscs for drug delivery, focusing on design strategies, functionalization methods, and key challenges for potential clinical translation.

Thirupathi Ravula, C. N. Obi, A. Ramamoorthy · 0 citations

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