Thomas Candela

Elucidating the pleiotropic effects of clpC deletion in Clostridioides difficile: proteomic and phenotypic insights.

Clostridioides difficile is a major cause of antibiotic-associated diarrhea and a significant public health threat. During its infectious cycle, C. difficile encounters various stresses within the gastrointestinal tract. Clp proteases play a crucial role in bacterial stress responses and protein homeostasis. In this st...