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Thomas Dupic

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Sep 2026

On inferring epistatic complexity in protein sequence-function landscapes.

The extent to which epistatic interactions create complexity in protein sequence-function landscapes is highly contested. Numerous empirical studies have found evidence for complex landscapes with widespread high-order epistasis. However, recent work has argued that many of these empirical sequence-function landscapes...

Thomas Dupic, Angela M. Phillips, M. M. Desai · 0 citations

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