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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Thomas Ipoutcha

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Open access Sep 2026

Mobile genetic elements drive a plasmid fusion and deletion lifecycle shaping evolution and antimicrobial resistance

Plasmids are key drivers of bacterial adaptation, yet the mechanisms that generate their diversity remain poorly understood. Here, we show that mobile genetic elements (MGEs) orchestrate a fusion-deletion life cycle that repeatedly remodels plasmids in Staphylococcus aureus . Large-scale genomic analyses reveal t...

Thomas Ipoutcha, Yi-Qing Wang, Eduardo P. C. Rocha et al. · 0 citations

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