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Author

Thomas J. LaRocca

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Open access Sep 2026

Biomechanical strain alters the microRNA cargo of primary myogenic cell-derived extracellular vesicles associated with a differentiation phenotype

Extracellular vesicles (EVs) are membrane-bound vesicles that regulate intercellular signaling by transporting cellular cargo including RNAs, proteins, and lipids. In recent years, EVs have emerged as promising biologic therapeutics for musculoskeletal repair, recapitulating many of the benefits of mesenchymal stromal...

K. Williams, L. Chubb, Shelby C. Osburn et al. · 0 citations
Open access Sep 2026

Apigenin Improves Healthspan and Protects Against Alzheimer’s Disease-Associated Proteotoxicity in C. elegans

Results support apigenin as a potential healthspan-promoting intervention that acts in part through reductions in oxidative stress-associated signaling, with beneficial effects that extend to models of Alzheimer’s disease-associated proteotoxicity.

Randy A. Grant, Lauren H. E. Park, Devin Wahl et al. · 0 citations

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