Thomas R. Covey

Acoustic Ejection Native Mass Spectrometry for High-Throughput Protein-Ligand Screening.

AEMS coupled to a high-resolution QTOF mass spectrometer as a high-throughput platform for nMS screening is demonstrated and acoustic ejection nMS is a practical high-throughput screening platform that simultaneously delivers direct molecular information on protein-ligand binding, binding stoichiometry, and protein oli...