Author

Thomas Robert

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Open access Sep 2026

Mammalian condensin I controls higher-order chromosome organization and homologous recombination in meiotic prophase I

The meiotic chromosome structure, defined by the axis-chromatin loop organization, is essential for proper homologue synapsis through the formation of the synaptonemal complex, and faithful homologous recombination. Here, we show that the conserved SMC-condensin I complex, which shapes the genome through chromatin loop...

Laurine Dal Toe, Boubou Diagouraga, A. Nore et al. · bioRxiv · 0 citations

Open access Sep 2026

Chromatin remodeling coordinates chromosome compaction, synaptonemal complex architecture and meiotic crossing-over

Crossing-over between maternal and paternal chromosomes during meiosis relies on the maturation of recombination intermediates within the synaptonemal complex (SC). These events unfold within a hierarchically organized environment, in which linear arrays of chromatin loops are anchored to the axes of meiotic chromosome...

Joao Matos, N. Palmer, Uladzislava Khauratovich et al. · Research Square · 0 citations