Open access
Oct 2026
Innate sensor responses set a supra-unitary threshold for viral replication.
Cells resist viral infection by triggering rapid and sensitive innate immune responses, initiated by cytoplasmic viral sensor proteins (CyVSP), retinoic acid-inducible gene I (RIG-I), melanoma differentiation-associated protein 5 (MDA-5), and protein kinase R (PKR). Our single-cell analysis reveals that viral replicati...
Kojiro Mukai, D. Jia, Mamata Panigrahi et al.
· Cell · 0 citations