Sep 2026
Gain-of-function suppressors restore microtubule dynamics and rescue dominant-negative tubulinopathies
Kai-Ming Xu, Zheng-Yang Guo, Jin-Ju Ke et al.
· Nature Cell Biology · 0 citations
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Aug 2026
ALKBH3 is an NPM1-dependent nucleolar protein required for rRNA biogenesis and translation.
The nucleolus is a membraneless nuclear organelle formed by liquid-liquid phase separation and serves as the hub for ribosomal RNA (rRNA) transcription and ribosome assembly. Here, we identify ALKBH3, a Fe(II)/α-ketoglutarate-dependent dioxygenase, as a previously unrecognized nucleolar protein that colocalizes with th...
Xixi Ma, Yuliang Huang, Hao Jin et al.
· Journal of Molecular Cell Bi... · 0 citations