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Tian-Kui Shuai

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Sep 2026

USP14-mediated deubiquitination of KRT19 promotes pyroptosis in myocardial ischemia/reperfusion injury.

BACKGROUND Myocardial ischemia/reperfusion (MI/R) injury remains a major clinical challenge characterized by inflammation and progressive cardiomyocyte loss. Although pyroptosis is known to drive this pathogenesis, the upstream molecular switches that trigger the pyroptotic cascade remain poorly understood. Here, we in...

Xiao-Wei Niu, Peng Lei, Tian-Kui Shuai et al. · 0 citations

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