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Tian-Lang Liu

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Oct 2026

Structural evolution of an ancient nucleotidyltransferase underlies divergence of AbiE antitoxins.

Type VII toxin-antitoxin (TA) systems neutralize toxins through antitoxin-mediated post-translational modification (PTM), with the oligoAMPylation-based HepT/MntA and phosphorylation-based AbiE systems representing the most prevalent families. Although the AbiE TA system from Mycobacterium tuberculosis is known to empl...

Tian-Lang Liu, Ran Chen, Kai-Hao Tang et al. · 0 citations

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