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Tian-Qing Zhang

3 papers indexed here

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Open access Aug 2026

NR4A1 Regulates Glycolysis in M1 Macrophages via the Wnt/β-Catenin Pathway to Affect Sepsis-Induced Myocardial Injury

Objective Pro-inflammatory M1 macrophage impede myocardial repair, and glycolysis plays a role in the pathological process of myocardial injury induced by M1 macrophage polarization. This study aims to elucidate the molecular mechanism by which NR4A1 participates in sepsis‑induced myocardial injury (SIMI) through regul...

Bo Sun, Yin-Huan Lu, Meng-Yuan Chen et al. · 0 citations
Review Open access Aug 2026

NLRP3 inflammasome in cardiovascular diseases: molecular mechanisms and advances in targeted drug research

The NLRP3 inflammasome plays a pivotal role in innate immune responses and has emerged as an important contributor to the pathogenesis of cardiovascular diseases (CVDs), including atherosclerosis, heart failure, myocardial infarction, and hypertension-related organ damage. Upon activation, NLRP3 promotes the maturation...

Tian-Qing Zhang, Li Luo, Kai-Lin Yang et al. · 1 citation

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