Objective Pro-inflammatory M1 macrophage impede myocardial repair, and glycolysis plays a role in the pathological process of myocardial injury induced by M1 macrophage polarization. This study aims to elucidate the molecular mechanism by which NR4A1 participates in sepsis‑induced myocardial injury (SIMI) through regul...
Bo Sun, Yin-Huan Lu, Meng-Yuan Chen et al.· Journal of Inflammation Rese...· 0 citations
The NLRP3 inflammasome plays a pivotal role in innate immune responses and has emerged as an important contributor to the pathogenesis of cardiovascular diseases (CVDs), including atherosclerosis, heart failure, myocardial infarction, and hypertension-related organ damage. Upon activation, NLRP3 promotes the maturation...
Tian-Qing Zhang, Li Luo, Kai-Lin Yang et al.· Frontiers in Immunology· 1 citation
These findings establish gliadin-fucoidan macromolecular assembly as a pH-responsive and biologically functional oral nanoplatform for renal inflammation.
Bo Sun, Yuan Zhuang, Wu-Yan Qian et al.· International Journal of Bio...· 0 citations
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