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Open access Sep 2026

Large-scale pleiotropic analysis across cancers reveals shared genetic mechanisms and identifies novel functional genes

Using summary statistics from genome-wide association studies for 37 cancer types, extensive genome-wide and local genetic correlations among cancers are identified and 33 novel functional genes harboring previously unreported cancer risk variants are identified.

Xiao-Hong Wu, Yu-Qing Yan, Wen Cao et al. · 0 citations

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