Author

Tian-Xue Han

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Open access Oct 2026

A folate receptor–targeted NIR-II probe improves intraoperative imaging and surgery of metastatic ovarian cancer

Intraoperative fluorescence imaging holds great promise for achieving complete cytoreduction in ovarian cancer, but its clinical utility is currently constrained by the limitations of existing imaging agents. In particular, the leading clinical probe, OTL38, operates in the near-infrared I (NIR-I; 700 to 1000 nanometer...

Wan-Ying Li, Zi-Mu Yuan, Shi-Qi Bai et al. · Science Advances · 0 citations

Review Oct 2026

Bioorthogonal chemistries for theranostics and radioconjugates.

The integration of diagnostic imaging and targeted therapy into unified theranostic platforms represents a paradigm shift in precision medicine. Yet, clinical efficacy is often hampered by suboptimal pharmacokinetics that impair target-specific uptake and increase systemic exposure, representing a persistent obstacle t...

Kaiwen Zhang, Tian-Xue Han, J. Pei et al. · Advanced Drug Delivery Revie... · 0 citations