Author

Tian Yu

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Aug 2026

YAP1-Driven PLCβ1 Impairs MHC-I Antigen Presentation and Limits Anti-Tumor Immunity in Gastrointestinal Cancer.

The YAP1-PLCβ1-MHC-I axis is uncovered as a critical mechanism of immune escape and combinatorial YAP inhibition is proposed as a promising strategy to sensitize gastrointestinal tumors to immunotherapy.

Ying-Jing Zhang, Peng-Fei Su, Tian Yu et al. · Cancer Research · 0 citations