Tian-Zhen Hua

Interleukin-33/IL-1RL1 axis modulates dendritic cell immune responses during the early phase of sepsis via RETREG1-mediated reticulophagy.

INTRODUCTION Interleukin-33 (IL-33) is a damage-associated alarmin that may have a profound effect on systemic inflammation. Dendritic cells (DCs) are critically involved in sepsis progression, but the precise regulation of DC function by IL-33 remains unresolved. OBJECTIVES This study explored the role of the IL-33...