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Author

Tiande Bing

1 paper indexed here

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Jul 2026

Discovery of Potent and Selective THRβ Agonists Based on an N-Benzoylglycine Scaffold for the Treatment of Metabolic Disorders.

An N-benzoylglycine scaffold is designed as a new chemotype, which provides selectivity for the THRβ receptor against THRα while preserving key interactions with the arginine-rich positively charged pocket and establishes the N-benzoylglycine scaffold as a promising chemotype for developing selective, orally active THR...

Yue Wu, Linjian Zhang, Xiao Li et al. · 0 citations

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