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Author

Tianhao Wu

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Open access Aug 2026

Hypoxia drives ERO1A-dependent angiogenesis in ovarian cancer cells promotes peritoneal metastasis and platinum resistance

High-grade serous ovarian cancer (HGSOC) is characterized by early peritoneal dissemination and frequent platinum resistance, yet the epithelial states and mechanisms that couple metastasis, angiogenesis, and therapy response remain incompletely defined. We integrated in-house single-cell RNA sequencing of 82,149 cel...

Si-Yang Zhang, Yu-Tong Liu, Xinyi Wang et al. · 0 citations
Open access Jul 2026

Demethylase ALKBH5 inhibits proliferation and promotes apoptosis of hepatocellular carcinoma cells by decreasing methylation levels and regulating SOCS3/STAT3 signaling.

It is suggested that ALKBH5, as a demethylase, suppresses HCC cell proliferation and promotes apoptosis by reducing methylation levels and modulating the SOCS3/STAT3 pathway.

Tianhao Wu, Zhen Yang, Jian-Sheng Chen et al. · 0 citations

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