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Author

Tiantain Xu

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Sep 2026

DRAM1 activates microglial pyroptosis and neuroinflammation through TMEM9-mediated lysosomal membrane permeabilization after spinal cord injury.

Spinal cord injury (SCI) is a devastating condition characterized by severe neuroinflammation and microglial pyroptosis, yet the underlying mechanisms remain incompletely understood. In this study, the role of DRAM1, a lysosomal membrane protein, in SCI pathogenesis was investigated. Single-cell RNA sequencing, an in v...

Zhi-Chao Xiong, Guang-Kui Yan, Jin-Fa Wu et al. · 0 citations

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