Open access
Aug 2026
Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer
ABSTRACT Poly(A)‐binding proteins (PABPs) are frequently dysregulated in cancers, yet their functional roles remain largely elusive. Here, we identify that PABPC4, a member of PABPs, is upregulated during colorectal cancer (CRC) progression and associated with poor prognosis. Single‐cell transcriptomics reveals that PA...
Meng Wang, Fang Yang, Yuan Gao et al.
· Advancement of science · 0 citations