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Author

Tibor Peňaška

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Open access Sep 2026

Improvements in the Total Synthesis of Ruxolitinib Through Mechanochemistry, Microwave Irradiation, and Green Solvents.

Syntheses of highly structurally complex compounds such as pharmaceuticals belong among the most demanding from a sustainability point of view. Herein, we present the total synthesis of an important pharmaceutical, ruxolitinib, through the strategic application of mechanochemistry, microwave irradiation, and green solv...

Zuzana Mravíková, Tibor Peňaška, Kveta Vargová et al. · 0 citations
Review Sep 2026

Recent Progress in Mechanochemical Organocatalysis

Mechanochemical activation has emerged as a powerful enabling strategy for sustainable organic synthesis, offering reduced solvent consumption, shorter reaction times, and access to reactivity patterns that may differ from conventional solution chemistry. This review summarizes recent progress in mechanochemical organo...

Tibor Peňaška, Zuzana Mravíková, Mária Mečiarová et al. · 0 citations

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