Glycans encode critical biological information through variations in monosaccharide composition, branching architecture, and chemical modifications. However, decoding these structural features with single-monosaccharide precision at physiological (nM–µM) concentrations remains a major challenge. Herein, we develop a re...
Hui Ma, Ya-Xu Li, Zhuo-Jia Xu et al.· Chemical Science· 0 citations
Legionaminic acid (Leg) is a bacteria‐specific nonulosonic acid that has emerged as a promising target for the development of pathogen diagnostics and vaccines, especially against critical‐priority
Acinetobacter baumannii
. However, immunological studies of Leg‐containing glycoconjugates remain largely unexplored...
Zhuo-Jia Xu, Xiang-Yu Wang, Hua-Jie Zhang et al.· Chinese journal of chemistry· 0 citations
N- and O-glycosylations are essential post-translational modifications involved in numerous physiological and pathological processes. Sulfated N- and O-glycans, commonly found on biologically important glycoproteins, serve as critical mediators of molecular recognition. However, their precise structure-function relatio...
