Tie-Suo Zhao

The APC/C subunit APC7 exerts antiviral effects by targeting the adaptor protein MAVS

The innate immune response is the first line of host defense against viral infection. RNA virus infection triggers activation of retinoic acid-inducible gene-I (RIG-I)-mitochondrial antiviral signaling protein (MAVS) signaling pathway, resulting in the formation of prion-like aggregates of MAVS and production of type I...