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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Tim-Oliver Buchholz

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Open access Jul 2026

Live single-molecule imaging reveals global shifts in mRNA mobility during human stem cell differentiation

A robust pipeline for MS2 tagging of endogenous transcripts in human induced pluripotent stem cells is established, coupled with single-particle tracking and Hidden Markov Modelling to map mRNA mobility landscapes during differentiation and cell state transitions, revealing a conserved principle.

Aileen-Diane Bamford, Gilles Gut, Tim-Oliver Buchholz et al. · 0 citations

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