Open access
Sep 2026
Lethal C57BL/6 mouse model for Yezo virus infection and antiviral therapeutic evaluation
ABSTRACT Yezo virus (YEZV) is an emerging tick-borne orthonairovirus that causes febrile illness and hepatic injury in humans. However, its pathogenesis and effective antiviral interventions remain poorly characterized. In this study, we generated a lethal, mouse-adapted YEZV strain through 30 serial passages in C57BL/...
Yu Liu, Ning Liu, Ge-Lin Zhang et al.
· Emerging Microbes and Infect... · 0 citations