Jul 2026
Diverse bioactive metabolites from Callicarpa longifolia var. floccosa: terpenoids, polyketide, and callilongiflocin A as a potent anti-inflammatory diterpenoid targeting IL-17/TNF-α/MAPK signaling with anti-psoriatic activity.
Callilongiflocin A (1) exhibited the most potent effects, significantly suppressing the production of NO, pro-inflammatory cytokines interleukin (IL)-6 and tumor necrosis factor-α (TNF-α), and the overexpression of inducible NO synthase (iNOS) in a concentration-dependent manner.
Ting Liu, Xiao-Lu Wu, Lianchun Li et al.
· Phytochemistry · 0 citations