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Open access Sep 2026

Multi-omics analyses reveal cellular responses to biosynthesis of the non-natural cofactor nicotinamide cytosine dinucleotide

The ubiquitous cofactors nicotinamide adenine dinucleotide (NAD) and its reduced form play pivotal roles in energy metabolism and redox homeostasis. Recently, an NAD analog nicotinamide cytosine dinucleotide (NCD) has emerged for selective energy transfer in vivo . However, the biological effects of NCD remain elus...

Xiao-Jia Guo, Qian Wang, Ting Liu et al. · 0 citations

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