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Ting-Ting Tan

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Review Open access Aug 2026

Bone formation niche dysfunction in osteoporosis: insights from single-cell and spatial transcriptomic studies

Bone formation is spatially organized, yet the molecular architecture of the bone formation niche has only recently become accessible. Osteoporosis is a major skeletal disorder characterized by bone loss, microarchitectural deterioration, and increased fracture risk. Although antiresorptive and anabolic therapies are e...

Ting-Ting Tan, Xiao-Ning Guo, Zheng-Xiao Ouyang · 0 citations

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